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Dr. Kuo have experiences in several engineering disciplines. 
His industrial experiences in environmental engineering include water and wastewater treatment, design and installation of air strippers, activated carbon adsorbers, flare/catalytic incinerator, bioremediation systems, and soil venting systems for wastewater treatment as well as groundwater/soil remediation; site assessment and fate analysis of toxics in the environment; RI/FS work for landfills and Superfund sites; design of flanged joints to meet the stringent fugitive emission requirements.  His areas of researches in environmental engineering include dechlorination of halogenated aromatics by ultrasound, fines/bacteria migration through porous media, biodegradability of bitumen, surface properties of composite mineral oxides, kinetics of activated carbon adsorption, and wastewater filtration, nutrient removal, and disinfection. His recent research areas include methane emission testing for natural gas and crude oil industries, emission reductions of greenhouse gases, using nanoparticles for water/wastewater treatment, nutrient removal in wastewater treatment, membrane biological removal processes, disinfection of reclaimed water, landfill gas recovery and energy generation, and stormwater runoff treatment and management. Dr. Kuo also patented a process for separation of heavy crude from tar sands by using ultrasound irradiation.